UMIN ID: UMIN000008250
Registered date:01/07/2012
Visceral fat and adipocytokine profile in Japanese patients with type2 diabetes mellitus treated with DPP-4 inhibitors.
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Type 2 diabetes |
| Date of first enrollment | 2012/08/01 |
| Target sample size | 50 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Alogliptin 25mg Pioglitazone 15mg-30mg Metformin 500mg-2250mg |
Outcome(s)
| Primary Outcome | Decrement of visceral fat area/ visceral fat/subcutaneous fat rate, Change in adipocytokine/PWV |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | 30years-old |
|---|---|
| Age maximum | 80years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1) Patients who were added other OADs during the course of the trial. 2) Patients on corticodteroid. 3) Patients with renal impairment or moderate to severe hepatic dysfunction. 4) Patients with heart failure. 5) Patients treated with insulin or who absolutely needs insulin treatment. 6) Patients with current malignancy. 7) Patients with endocrine disorders. 8) Patients with severe mental illness. 9) Patients with pregnancy or lactating. 10) An excessive alcohol drunker. 11) Patients under the contraindication of each drugs. |
Related Information
| Primary Sponsor | Kawasaki Medical School Hospital |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | None |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Mitsuru Hashiramoto |
| Address | 577 Matsushima, Kurashiki 701-0192, Japan Japan |
| Telephone | 086-462-1111 |
| hashira@med.kawasaki-m.ac.jp | |
| Affiliation | Kawasaki Medical School Hospital Division of Diabetes, Endocrinology and Metabolism |
| scientific contact | |
| Name | Tomoatsu Mune |
| Address | 577 Matsushima, Kurashiki 701-0192, Japan Japan |
| Telephone | |
| Affiliation | Kawasaki Medical School Hospital Division of Diabetes, Endocrinology and Metabolism |