UMIN ID: UMIN000004150
Registered date:02/09/2010
The effect of remifentanil on cardiac conduction system in pediatric patients undergoing radiofrequency catheter ablation
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Wolff-Parkinson-White syndrome |
| Date of first enrollment | 2009/04/01 |
| Target sample size | 60 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Remifentanil 0.2 microg/kg/min Remifentanil 0.4 microg/kg/min |
Outcome(s)
| Primary Outcome | After anesthetic induction and catheter insertion, CSACT (calculated sinoatrial conduction time) is measured during first EPS (electrophysiological study). And then, remifentanil is administered at a rate of 0.2 or 0.4 microg/kg/min. Almost 10 minutes after remifentanil administration, second EPS and CSACT measurement is performed. |
|---|---|
| Secondary Outcome | As with mentioned above, CSNRT (corrected sinus node recovery time), RR interval, and AH interval are measured before and during remifentanil administration. |
Key inclusion & exclusion criteria
| Age minimum | 3years-old |
|---|---|
| Age maximum | 16years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | Exclusion criteria 1) obesity 2) allergy to the trial or companion drugs 3) previous history of kidney, and/or liver disease. 4) patients with severe heart diseases including cardiomyopathy, valvulopathy, and congenital cardiac diseases 5) patients deemed unsuitable for the study by investigators |
Related Information
| Primary Sponsor | Department of Anesthesiology Japanese Red Cross Society Wakayama Medical Center |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | None |
| Secondary ID(s) |
Contact
| public contact | |
| Name | |
| Address | Japan |
| Telephone | 073-422-4171 |
| Affiliation | Japanese Red Cross Society Wakayama Medical Center Department of Anesthesiology |
| scientific contact | |
| Name | Hiroshi Iranami |
| Address | Komatsubara-dori 4-20, Wakayama 640-8558, Japan Japan |
| Telephone | 073-422-4171 |
| Affiliation | Japanese Red Cross Society Wakayama Medical Center Department of Anesthesiology |