UMIN ID: UMIN000003258
Registered date:01/04/2010
The evaluation of intestinal permeability for damage of mucosal injury from NSAIDS
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Volunteer |
| Date of first enrollment | 2010/04/01 |
| Target sample size | 10 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Dicrofenac sodium 25mg 3times/day +Placebo 3times/day +Omeprazole20mg/day for 7days Dicrofenac25mg 3times/day +Rebamipide300mg/day +Omeprazole20mg/day for 7days |
Outcome(s)
| Primary Outcome | To evaluate the correlation between various sugars permeability of Stomach, Small intestine and Large intestine and injury by observation of CE |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | 60years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1) Patients who have allergy for study drugs. 2) Patients who got intestinal operation. 3) Patients who suffer from ileus. 4) Patients who fit the pacemaker. 5) Patients who take calcium antagonist, nitrous acid drug, NSAIDS, anti ulcer drug, and alcohol ordinary before 2weeks. 6) Patients who have diabetes. 7) Patients who have renal failure and liver failure. 8) Patients who have heart failure. 9) Patients who have (have been suspected) renal infection. 10) Patients whom doctor judged as inadequate. |
Related Information
| Primary Sponsor | Aichi Medical University |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Aichi Medical University |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Makoto Sasaki |
| Address | 21, Karimata, Yasagoaza, Ooaza, Nagakute-cho, Aichi-gun, Aichi 480-1195, Japan |
| Telephone | +81-561-62-3311 |
| msasaki@aichi-med-u.ac.jp | |
| Affiliation | Aichi Medical University Gastroenterology |
| scientific contact | |
| Name | Makoto Sasaki |
| Address | 21, Karimata, Yasagoaza, Ooaza, Nagakute-cho, Aichi-gun, Aichi 480-1195, Japan |
| Telephone | +81-561-62-3311 |
| Affiliation | Aichi Medical University Gastroenterology |