Evaluation of usefullness of 1H MR spectroscopy for diagnosis of breast tumors.

UMIN ID: UMIN000002462

Registered date:09/09/2009

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: breast tumor
• Date of first enrollment: 2009/10/01
• Target sample size: 140
• Countries of recruitment: Japan
• Study type: Interventional
• Intervention(s): We will perform 1H MR spectroscopy to the patients of the breast cancer and measure the density of choline compounds which related to the composition and metabolism of the phospholipid of cell membrane. In addition, we will use the density of choline compounds as a marker for differential diagnosis of the breast cancer from benign tumors; phylodes tumor, papilloma and fibrocystic disease.

Outcome(s)

• Primary Outcome: Measurement of density of choline compounds and tumor size before treatment

Key inclusion & exclusion criteria

• Age minimum: Not applicable
• Age maximum: Not applicable
• Gender: Female
• Exclude criteria: 1) The patient who has any contraindication on MRI 2) The patient who cannot be taken contrast material of MRI. 3) The patient who has been taken biopsy of the breast tumor 4) The patient who ever has been taken surgery, chemotherapy, radiation or any other therapy for the breast tumor.

Related Information

• Primary Sponsor: International medical center, Saitama medical university
• Source(s) of Monetary Support: International medical center, Saitama medical university