NIPH Clinical Trials Search

UMIN ID: UMIN000002383

Registered date:25/08/2009

Feasibility study of adjuvant chemotherapy with S-1 in elderly patients with non-small-cell lung cancer

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiednon-small-cell lung cancer
Date of first enrollment2009/04/01
Target sample size25
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)Adjuvant chemotherapy of eight courses (2-week administration and 1-week withdrawal): S-1 dose of 67mg/m2 twice daily


Primary OutcomeThe percentage of patients who accomplished S-1 therapy of eight courses.
Secondary OutcomeAdverse events The relative total administration dose of S-1

Key inclusion & exclusion criteria

Age minimum70years-old
Age maximumNot applicable
GenderMale and Female
Include criteria
Exclude criteria1)Past history of drug hypersensitivity 2)Past history of myocardial infarction within 6 months 3)Interstitial pneumonia or active lung fibrosis 4)Uncontrolled heart diseases 5)Uncontrolled psychiatric disorders 6)Uncontrolled diabetes 7)Bowel problems 8)Active infection 9)Severe complications 10)Active concomitant malignancy

Related Information


public contact
Name Noriyuki Ebi
Address Japan
Telephone 0948-22-3800
Affiliation Iizuka Hospital Department of respiratory medicine
scientific contact
Name Yukito Ichinose
Address Fukuoka Japan
Telephone 092-541-3231
Affiliation National Kyushu Cancer Center Department of Thoracic Oncology