NIPH Clinical Trials Search

UMIN ID: UMIN000002317

Registered date:10/08/2009

A phase III randomised trial of lobectomy versus limited resection (segmentectomy) for small (2 cm or less) peripheral non-small cell lung cancer (JCOG0802/WJOG4607L)

Basic Information

Recruitment status Complete: follow-up continuing
Health condition(s) or Problem(s) studiedsmall (2 cm or less) peripheral non-small cell lung cancer
Date of first enrollment2009/08/10
Target sample size1100
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)A: Pulmonary lobectomy B: Pulmonary segmentectomy


Primary Outcomeoverall survival
Secondary Outcomepostoperative respiratory function, relapse-free survival, proportion of local recurrence, adverse events, proportion of completion of segmentectomy, days of hospitalization, duration of chest tube placement, operation time, blood loss, number of used auto-sutures.

Key inclusion & exclusion criteria

Age minimum20years-old
Age maximum85years-old
GenderMale and Female
Include criteria
Exclude criteria1) Active bacterial or fungous infection. 2) Simultaneous or metachronous (within the past 5 years) double cancers. 3) Women during pregnancy or breast-feeding. 4) Interstitial pneumonitis, pulmonary fibrosis, or severe pulmonary emphysema. 5) Psychosis. 6) Systemic steroids medication. 7) Uncontrollable diabetes mellitus. 8) Uncontrollable hypertension. 9) History of severe heart disease, heart failure, myocardial infarction within the past 6 months or attack of angina pectoris within the past 6 months.

Related Information


public contact
Name Masahiro Tsuboi / Hisashi Saji
Address 1-1-2, Nakao, Asahi-ku, Yokohama, 241-0815, JAPAN / 2-16-1, Sugao, Miyamae-ku, Kawasaki, 216-8511 Japan
Telephone (045)-391-5761(044)-977-8111
Affiliation JCOG0802 Study Coordinating Office Division of Thoracic Surgery, Kanagawa Cancer Center/St. Marianna University School of Medicine Hosp
scientific contact
Name Hisao Asamura
Address Shinanomachi 35, Shinjuku-ku, Tokyo 160-8582, JAPAN Japan
Telephone 03-5363-3805
Affiliation Keio University School of Medicine Division of Thoracic Surgery