UMIN ID: UMIN000002292
Registered date:10/08/2009
Substudy of lipid lowering trial on prevention of atherosclerosis in 75 or older on cholesterol absorption and synthesis
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Hyper-LDL-cholesterolemia |
| Date of first enrollment | 2009/08/01 |
| Target sample size | 1000 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | ezetimibe and diet diet |
Outcome(s)
| Primary Outcome | 0 to 24weeks (1)changes in cholesterol absorption and synthesis (2)changes in inflammation markers (3)changes in lipoproteins(RLPcholesterol, small dense LDL etc), oxydised phospholipid, oxdised cholesterol) (4)NT-proBNP |
|---|---|
| Secondary Outcome | relation to composite cardiovascular events (same as EWTOPIA75) |
Key inclusion & exclusion criteria
| Age minimum | 75years-old |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | same as EWTOPIA75 |
Related Information
| Primary Sponsor | International University of Health and Welfare |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | International University of Health and Welfare |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Jun Sasaki, MD.PhD |
| Address | 1-3-1 Nagahama Chuoo-ku, Fukuoka, Japan Japan |
| Telephone | 092-711-1126 |
| fukuoka-shiken@iuhw.ac.jp | |
| Affiliation | EWTO75-Kyushu group EWTOPIA-Kyushu group office |
| scientific contact | |
| Name | Jun Sasaki, MD,PhD |
| Address | 1-3-1 Nagahama Chuoku, Fukuoka, Japan Japan |
| Telephone | 092-711-1126 |
| Affiliation | International University of Health and Welfare Pharmaceutical Medicine |