Disinfection rate for intravitreal injection and

UMIN ID: UMIN000002260

Registered date:01/04/2013

Basic Information

• Recruitment status: Complete: follow-up continuing
• Health condition(s) or Problem(s) studied: Choroidal neovascularization, retinal vein occlusion, diabetic retinopathy
• Date of first enrollment: 2008/10/01
• Target sample size: 130
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Disinfection with 5% povidone iode for conjunctiva and 10% povidone iode for lid
0.5% levofloxacin eye drops weer applied every 5 minutes 3 times, and then 1.25% povidon iode eyd drops applied every minute 3 times as well as 10% povidone iode for lid

Outcome(s)

• Primary Outcome: Disinfection rate of the conjunctival sac before injection,
• Secondary Outcome: culture positive rate of the injection needle after injection

Key inclusion & exclusion criteria

• Age minimum: 20years-old
• Age maximum: Not applicable
• Gender: Male and Female
• Exclude criteria: 1) Intravitreal steroid injection 2) immunocompromised 3) any difficulties when injection 4) any in appropreate condition judged by the physician 5) Atopic dermatitis 6) Iode or levefloxacin allergy 7) Disagreed patients 8) any antibiotic treatment within last 2 weeks

Related Information

• Primary Sponsor: Department of Ophthalmology, Osaka University Medical School
• Source(s) of Monetary Support: NA