UMIN ID: UMIN000002241
Registered date:01/08/2009
Pilot study searching neural correlates of changes in social impairments induced by intranasal oxytocin administration in subjects with autism spectrum disorder
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Autism spectrum disorder |
| Date of first enrollment | 2009/09/01 |
| Target sample size | 20 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Single intranasal administration of 24 units oxytocin (Syntocinon spray) Single intranasal administration of placebo |
Outcome(s)
| Primary Outcome | Bold signal changes of functional Magnetic Resonance Imaging |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | 18years-old |
|---|---|
| Age maximum | 55years-old |
| Gender | Male |
| Include criteria | |
| Exclude criteria | 1) History of allergy for oxytocin 2) Cannot enter Magnetic Resonance Scanner 3) History of traumatic brain injury with any known cognitive consequences or loss of consciousness for more than 5 minutes 4) History of substance abuse or addiction 5) Instabilized with psychiatric comorbidity |
Related Information
| Primary Sponsor | Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Japan Science and Technology Agency |
| Secondary ID(s) |
Contact
| public contact | |
| Name | |
| Address | Japan |
| Telephone | |
| Affiliation | The University of Tokyo Hospital Clinical Research Center |
| scientific contact | |
| Name | Hidenori Yamasue |
| Address | 7-3-1 Hongo, Bunkyo-ku, Tokyo Japan |
| Telephone | 03-5800-9263 |
| Affiliation | Graduate School of Medicine, University of Tokyo Department of Neuropsychiatry |