NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
UMIN ID: UMIN000002218

Registered date:17/07/2009

A randomized trial to assess the effects of hydrogen-ride dissolution water for the patients with mild cognitive impairment (MCI).

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedmild cognitive impairment
Date of first enrollment2009/07/01
Target sample size120
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)The patients of hydrogen group will be intervened with 500ml hydrogen dissolution water every-day for 2 years. The patients of placebo group will be intervened with 500ml ordinary water every-day for 2 years.

Outcome(s)

Primary OutcomeScore in Japanese version of ADAS-Cog and Mini Mental State Examination.
Secondary OutcomeScores in Japanese version of ADCS-ADL, MRI and SPCET imaging, and Geriatric Depression Scale.

Key inclusion & exclusion criteria

Age minimum67years-old
Age maximumNot applicable
GenderMale and Female
Include criteria
Exclude criteria1) Meeting DSM-IV TR criteria for dementing illnesses. 2) Having serious or unstable illnesses. 3) Having a history within past 5 years of serious infectious disease affecting the brain and/or malignant diseases. 4) Having a history of alcohol or drug abuse or dependence (on DSM-IV TR) within the past 5 years. 5) Receiving any types of anti-Alzheimer drugs. 6) Recent (within 4 weeks) initiation of medications that affect the central nervous system.

Related Information

Contact

public contact
Name Takashi Asada
Address 1-1-1, Tennodai, Tsukuba City, Ibaraki-prefecture Japan
Telephone
E-mail tasada@md.tsukuba.ac.jp
Affiliation University of Tsukuba Department of Neuropsychiatry, Institute of Clinical Medicine
scientific contact
Name Takashi Asada
Address 1-1-1, Tennodai, Tsukuba City, Ibaraki-prefecture, Japan
Telephone +81(29)853-3178
E-mail
Affiliation University of Tsukuba Department of Neuropsychiatry, Institute of Clinical Medicine