UMIN ID: UMIN000002205
Registered date:15/09/2009
Investigation about treatment of midnight hypertension in diabetes
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | hypertension in diabetes |
| Date of first enrollment | 2009/09/01 |
| Target sample size | 40 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | olmesartan 20 mg +amlodipine 5mg once daily olmesartan 20 mg + azelnidipine 16 mg once daily candesartan 8 mg or varsartan 80 mg + amlodipine 5mg once daily candesartan 8 mg or varsartan 80 mg + azelnidipine 16 mg once daily |
Outcome(s)
| Primary Outcome | comparison of the anti-hypertensive effect through the 24 hrs |
|---|---|
| Secondary Outcome | change in urinary albumin excretion ratio |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | 79years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1) drug allergy to ARB or Ca antagonist 2) pregnant women or possible pregnant women 3) using anti-fugal drug or HIV protease inhibitor 4) bilateral renal artery stenosis or unilateral renal artery stenosis of remnant kidny |
Related Information
| Primary Sponsor | Division of diabetes, metabolism and Endocrinology Department od Internal Medicine, Kobe University Graduate School of Medicine |
|---|---|
| Secondary Sponsor | none |
| Source(s) of Monetary Support | none,none |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Kazuhiko sakaguchi |
| Address | 7-5-1 Kusunoki-cho, Chuo-ku, Kobe Japan |
| Telephone | 078-382-5861 |
| kzhkskgc@med.kobe-u.ac.jp | |
| Affiliation | Department od Internal Medicine, Kobe University Graduate School of Medicine Division of diabetes, metabolism and Endocrinology |
| scientific contact | |
| Name | Kazuhiko sakaguchi |
| Address | 7-5-1 Kusunoki-cho, Chuo-ku, Kobe Japan |
| Telephone | 078-382-5861 |
| kzhkskgc@med.kobe-u.ac.jp | |
| Affiliation | Department od Internal Medicine, Kobe University Graduate School of Medicine Division of diabetes, metabolism and Endocrinology |