A prospective randomized controlled trial of utility of antibiotic prophylaxis in patients after liver resection

UMIN ID: UMIN000002187

Registered date:13/07/2009

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: hepatocellular carcinoma, metastatic liver tumor, cholangiocarcinoma, liver tumor, biliary cancer, biliary tumor
• Date of first enrollment: 2009/07/01
• Target sample size: 100
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Administration of prophylactic antibiotic after liver resection
Non-administration of prophylactic antibiotic after liver resection

Outcome(s)

• Primary Outcome: septic complications (wound infection, infectious ascites, abdominal abscess, pneumonia, urinary infection, catheter infection)
• Secondary Outcome: the incidence of other postoperative complications, mortality,bile leakage, ascites, abdominal hemorrhage.

Key inclusion & exclusion criteria

• Age minimum: Not applicable
• Age maximum: Not applicable
• Gender: Male and Female
• Exclude criteria: 1) patients with severe complications which were possible to prolong hospital stay, 2) patients undergone hemodialysis, 3) patients combined resection of other organs, 4) patients who were diagnosed inadequacy for this study by a physician, and 5) patients without an informed consent

Related Information

• Primary Sponsor: Osaka Medical College
• Source(s) of Monetary Support: none