Evaluation of index for the diagnosis of asthma

UMIN ID: UMIN000002159

Registered date:03/07/2009

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: bronchial asthma
• Date of first enrollment: 2009/01/01
• Target sample size: 125
• Countries of recruitment: Japan
• Study type: Observational

Outcome(s)

• Primary Outcome: The following parameter of each index for the diagnosis of asthma; 1) Sensitivity(%) and Specificity(%) 2) PPV(Positive Predictive Value:%), NPV(Negative Predictive Value:%) 3) ROC curve (Receiver-Operator Characteristic curve) 4) Area under the ROC curve

Key inclusion & exclusion criteria

• Age minimum: 20years-old
• Age maximum: Not applicable
• Gender: Male and Female
• Exclude criteria: 1) Patient who used anti-inflammatory drugs (oral/inhaled/nasal steroid, leukotriene receptor antagonist, chemical mediator release inhibitor, Th2 cytokine inhibitor, or slow-release theophylline) within the past four weeks 2) Patient who was affected with respiratory tract infection within the past three weeks 3) Patient with a history of asthma 4) Patient with breast abnormality detected by a chest X-ray 5) Patient who occurs with the following pulmonary diseases: bronchiectasis, primary pulmonary cancer, connective tissue disease, pulmonary hypertension, and/or cystic disease of the lungs 6) Patient who smoked within the past year

Related Information

• Primary Sponsor: Dokkyo Medical University Koshigaya Hospital
• Source(s) of Monetary Support: Japan Allergy Foundation