UMIN ID: UMIN000002136
Registered date:02/07/2009
Safety, efficacy and immunogenicity of autologous tumor lysate-pulsed dendritic cell therapy in patients with advanced renal cell carcinoma
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Renal cell carcinoma |
| Date of first enrollment | 2009/07/01 |
| Target sample size | 15 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Tumor lysate-pulsed dendritic cell Sunitinib |
Outcome(s)
| Primary Outcome | Safety |
|---|---|
| Secondary Outcome | Immunological responses Antitumor effect Overall survival Progression-free survival |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | Patients who have: - Pulmonary fibrosis or interstitial pneumonia, or history or predisposition of them; - Serious drug allergy; - Active infections; - Serious cardiac disease; - Active autoimmune diseases; - Continuous systemic administration of steroids within 4 weeks; - Other cancers. |
Related Information
| Primary Sponsor | The University of Tokyo Hospital |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Medinet Co.,Ltd. |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Kazuhiro Kakimi |
| Address | 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8655, Japan Japan |
| Telephone | 03-5805-3161 |
| immunotherapy-admin@umin.ac.jp | |
| Affiliation | Graduate School of Medicine, The University of Tokyo Department of Immunotherapeutics |
| scientific contact | |
| Name | Yukio Homma |
| Address | 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8655, Japan Japan |
| Telephone | 03-5800-8662 |
| Affiliation | The University of Tokyo Hospital Department of Urology |