NIPH Clinical Trials Search

UMIN ID: UMIN000002081

Registered date:01/07/2009

preoperative combined chemothrapy with docetaxel, cisplatin and S-1 in local advanced gastric cancer; multicentric phase II study

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedlocal advanced gastric cancer (excluding T3-4, bulky N2 & N3 and giant type3 & type 4)
Date of first enrollment2009/07/01
Target sample size55
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)2 courses of DCS therapy followed by gastrectomy. docetaxel 35mg/m2/ D1, 8/ q4w cisplatin 35mg/m2/ D1, 8/ q4w S-1 80mg/m2/ D1-14/ q4w


Primary Outcomepathological response
Secondary Outcome

Key inclusion & exclusion criteria

Age minimum20years-old
Age maximum75years-old
GenderMale and Female
Include criteria
Exclude criteria1) obvious infection 2) severe complication 3) active other malignancies 4) distant metastases 5) motor palalysis or peripheral neuropathy 6) drug hypersensitivity 7) mental disorder 8) possibility of pregnancy 9) judged as unsuitable by the doctor in charge

Related Information


public contact
Name Sachio Fushida
Address 13-1 Takara-machi, Kanazawa Japan
Telephone 076-265-2362
Affiliation Kanazawa University Hospital Gastroenterological Surgery
scientific contact
Name Atsushi Nashimoto
Address 2-15-3 Kawagishi-chou, Niigata Japan
Telephone 025-266-5112
Affiliation Society for the study of DCS therapy Surgery, Niigata Cancer Center Hospital