UMIN ID: UMIN000002060
Registered date:10/06/2009
The Influence of Proton Pump Inhibitors on the Antiplatelet Effect of Clopidogrel
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | ischemic heart disease |
| Date of first enrollment | 2009/06/01 |
| Target sample size | 120 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | the change of administration from 20 mg of omeprazole to 10 mg of rabeprazole the change of administration from 10 mg of rabeprazole to 20 mg of omeprazole control |
Outcome(s)
| Primary Outcome | Maximal Platelet Aggregation Rate after intake of PPI |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | Not applicable |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1) contraindicative patients of aspirin and clopidogrel, 2) patients with warfarin, 3) patients with thrombolytic therapy within 2 weeks, and 4) patients taking ticlopidine, cilostazole or dipyridamole within 1 month |
Related Information
| Primary Sponsor | Department of Cardiovascular Medicine, Kyoto University |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | self funding |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Toshikazu Jinnai |
| Address | 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507 Japan |
| Telephone | 075-751-4255 |
| Affiliation | Kyoto University Department of Cardiovascular Medicine |
| scientific contact | |
| Name | Takeshi Kimura |
| Address | 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507 Japan |
| Telephone | 075-751-4254 |
| Affiliation | Kyoto University Department of Cardiovascular Medicine |