A randomised crossover study comparing tafluprost and travoprost in subjects with normal tension glaucoma of pseudophakic eye

UMIN ID: UMIN000002021

Registered date:15/06/2009

Basic Information

• Health condition(s) or Problem(s) studied: Normal tension glaucoma of pseudophakic eye
• Date of first enrollment: 2009/08/01
• Target sample size: 50
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Washout in treated with glaucoma medication for 1 month
Tafluprost or travoprost monotherapy 12 weeks treatment once a day

Outcome(s)

• Primary Outcome: Intraocular pressure reduction, % reduction of intraocular pressure
• Secondary Outcome: Safety

Key inclusion & exclusion criteria

• Age minimum: 20years-old
• Age maximum: Not applicable
• Gender: Male and Female
• Exclude criteria: 1; Patients with exfoliation glaucoma and neovascular glaucoma 2; Patients with diabetic retinopathy 3; Excessive myopia before cataract surgery(>-6D) 4; Patients with advanced visual field loss(>-15dB) 5; Any corneal abnormality or other condition preventing reliable applanation tonometry 6; Presence of any external ocular disease, uveitis or infection of the eye and/or eye lid 7; History of refractive surgery 8; History of laser trabeculoplasty, filtering surgery, trabeculotomy and vitorectomy 9; Pregnant, pregnant suspect, and nursing woman. Woman who is wishing pregnancy or preventing pregnancy 10; The Investigator declare any subject ineligible for any sound medical reasion

Related Information

• Primary Sponsor: MIzoguchi Eye Clinic
• Secondary Sponsor: Non
• Source(s) of Monetary Support: Non,Non