NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
UMIN ID: UMIN000002009

Registered date:26/05/2009

The Effect of genetic polymorphism of CYP2B6 and UGT1A9 on the Pharamcokinetics and Pharmacodynamics of Propofol

Basic Information

Recruitment status Complete: follow-up continuing
Health condition(s) or Problem(s) studiedThe patients are surgical operation with propofol in the St. Marianna University Hospital
Date of first enrollment2009/06/01
Target sample size100
Countries of recruitmentJapan
Study typeObservational
Intervention(s)

Outcome(s)

Primary OutcomeThe recovery of consciousness time, polymorphism of CYP2B6 and UGT1A9
Secondary OutcomePharmacokinetics parameter of propofol

Key inclusion & exclusion criteria

Age minimum20years-old
Age maximumNot applicable
GenderMale and Female
Include criteria
Exclude criteriaThe patients did not informed consent. The propofol administration dosage is varied. The patients are transfusion during surgical operation. The patients have infection. The patients is under the confusion, ileus, agnosis, resection of stomach, disorder of liver function, disorder of kidney function, suppress of breathing, chronic obstructive pulmonary disease, asthma, heart failure with chronic pulmonary disease, and/or seizure. The medical doctor is estimate that the patients cannot entry of study

Related Information

Contact

public contact
Name Toshio Kumai
Address 2-16-1 Sugao, Miyamae-ku, Kawasaki 216-8511 Japan Japan
Telephone 044-977-8111
E-mail kumai@marianna-u.ac.jp
Affiliation St. Marianna University School of Medicine Department of Pharmacogenomics
scientific contact
Name Toshio Kumai
Address 2-16-1 Sugao, Miyamae-ku, Kawasaki 216-8511 Japan Japan
Telephone 044-977-8111
E-mail kumai@marianna-u.ac.jp
Affiliation St. Marianna University School of Medicine Department of Pharmacogenomics