NIPH Clinical Trials Search

UMIN ID: UMIN000001962

Registered date:13/05/2009

Feasibility study of nonmyeloablative allogeneic stem cell transplantation as a consolidation after autologous peripheral blood stem cell transplantation for multiple myeloma with poor prognosis

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedMultiple myeloma
Date of first enrollment2009/07/01
Target sample size22
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)Nonmyeloablative allogeneic stem cell transplantation as a consolidation


Primary OutcomeCumulative incidence of nonrelapse mortality at 6 months
Secondary OutcomeEngraftment rates, regimen-related toxicities, chimerism on peripheral blood, term to hematopoietic recovery, response rates, overall survival rates at 2 years, progression free survival at 2 years, nonrelapse mortality rates at 2 years, incidence of acute GVHD, and incidence of chronic GVHD

Key inclusion & exclusion criteria

Age minimum20years-old
Age maximum65years-old
GenderMale and Female
Include criteria
Exclude criteria(1)Positive for HIV antibody, HBs antigen and/or HBe antigen (2)Pregnant or during breast feeding (3)Other active cancer (4)Active psychiatric disease (5)Active infection (6)Allergic history to drugs used in the present conditioning regimen or GVHD prophylaxis regimen. (7)Cases that physicians judged as inappropriate

Related Information


public contact
Name Yoshihiro Inamoto
Address 65 Tsurumai, Showa-ku, Nagoya, Aichi, Japan Japan
Telephone 052-744-2145
Affiliation Nagoya University Graduate School of Medicine Department of Hematology and Oncology
scientific contact
Name Isamu Sugiura
Address 50 Aza Hachiken Nishi, Aotake–Cho, Toyohashi, Aichi, Japan Japan
Telephone 0532-33-6111
Affiliation Toyohashi Municipal Hospital Division of Hematology