UMIN ID: UMIN000001950
Registered date:08/05/2009
The JOINT Study :Evaluation of effect and safty of Losartan/Hydrochlorothazide fixed dose combination for hypertensive patients
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Hypertension |
| Date of first enrollment | 2008/06/01 |
| Target sample size | 400 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Losartan/Hydrochlorothizide |
Outcome(s)
| Primary Outcome | Change in systolic and diastolic blood pressure after 3 months of treatment |
|---|---|
| Secondary Outcome | Change in home blood pressure, serum uric acid, microalbuminuria, BNP after 3 months of treatment Change in serum uric acid, microalbuminuria, BNP, medication cost after 6 months of treatment |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | 75years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | (1)Patiens with renal failure(serum creatinine >2.5 mg/dL (2)Patients with liver dysfunction [GPT(ALT) over three times the normal value] (3)Pregnant or possible pregnant women (4)Breast-feeding women (5)Patients who are considered not eligible for the study by the attending doctor due to medical reasons |
Related Information
| Primary Sponsor | Clinical practice of Hypertensive treatment study group |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | The Kidney Foundation,Japan |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Iwao Ohno |
| Address | 3-25-8 Nishi-Shinbashi Minato-ku Tokyo Japan |
| Telephone | 03-3433-1111 |
| i-ohno@jikei.ac.jp | |
| Affiliation | Jikei University School of Medicine Division of Kidney and Hypertension |
| scientific contact | |
| Name | Tatsuo Hosoya |
| Address | 3-25-8 Nishi-Shinbashi Minato-ku Tokyo Japan |
| Telephone | 03-3433-1111 |
| Affiliation | Jikei University School of Medicine Division of Kidney and Hypertension |