UMIN ID: UMIN000001948
Registered date:08/05/2009
The clinical study for the mechanism of pioglitazone-induced edema in patients with type 2 diabetes using a salt monitoring system
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Type 2 diabetes |
| Date of first enrollment | 2006/10/01 |
| Target sample size | 60 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | administration of pioglitazone (15mg/day) |
Outcome(s)
| Primary Outcome | Onset of edema |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | 75years-old |
| Gender | Female |
| Include criteria | |
| Exclude criteria | 1) Congestive heart failure or having a history of congestive heart failure 2) Severe ketosis, diabetic coma, or type 1 diabetes 3) Having a severe hepatic or renal dysfunction 4) Having a severe infection or injury, or during perioperative period 5) Having an allergic history of pioglitazone 6) Be pregnant or at risk of becoming pregnant 7) Receiving any diuretic medication 8) Evaluated as being inadequate by the physician-in-charge |
Related Information
| Primary Sponsor | Graduate School of Medicine, Yokohama City University |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Grants for the Strategic Research Project (K18005, K19004) of Yokohama City University |
| Secondary ID(s) |
Contact
| public contact | |
| Name | |
| Address | Japan |
| Telephone | |
| Affiliation | Graduate School of Medicine, Yokohama City University Department of Endocrinology and Metabolism |
| scientific contact | |
| Name | Yasuo Terauchi |
| Address | 3-9 Fukuura, Kanazawa-ku, Yokohama Japan |
| Telephone | |
| Affiliation | Graduate School of Medicine, Yokohama City University Department of Endocrinology and Metabolism |