UMIN ID: UMIN000001934
Registered date:02/05/2009
Evaluating amphiregulin in plasma for metastatic colorectal cancer treated with cetuximab based therapy
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | unresectable metastatic colorectal cancer |
| Date of first enrollment | 2009/03/01 |
| Target sample size | 100 |
| Countries of recruitment | Japan |
| Study type | Observational |
| Intervention(s) |
Outcome(s)
| Primary Outcome | disease control rate between higher and lower amphiregulin group |
|---|---|
| Secondary Outcome | response rate Time to progression Overall survival |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1,symptomatic brain metastasis 2,serious pleural effusion or ascites 3,active infection 4,uncontrolled heart disease, diabetes and hypertension 5,diarrhea, watery stool 6,uncontrolled colonic or small bowel disorder 7,intestinal pneumonia of lung fibrosis 8,pregnancy or lactation period |
Related Information
| Primary Sponsor | Kinki University School of Medicine, Department of medical oncology |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Kinki University School of Medicine, Department of medical oncology |
| Secondary ID(s) |
Contact
| public contact | |
| Name | |
| Address | Japan |
| Telephone | 0723-66-0221 |
| Affiliation | Kinki University School of Medicine Department of Medical Oncology |
| scientific contact | |
| Name | Kimio Yonesaka MD PhD |
| Address | 377-2 Ohno-Higashi, Osaka-Sayama-shi, Osaka, Japan Japan |
| Telephone | |
| Affiliation | Kinki University School of Medicine Department of Medical Oncology |