UMIN ID: UMIN000001911
Registered date:01/05/2009
Beneficial effect of Raloxifene on high turn-over bone in chronic hemodialysis patients
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | chronic kidney disease postmenopausal osteoporosis |
| Date of first enrollment | 2009/05/01 |
| Target sample size | 50 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | medication of Raloxifene |
Outcome(s)
| Primary Outcome | serum bone alkaline phosphatase (BAP) level serum bone-specific tartrate-resistant acid phosphatase (TRAP5b) level |
|---|---|
| Secondary Outcome | serum levels od iPTH, calcium, phosphate, total cholesterol, and triacylglyceride |
Key inclusion & exclusion criteria
| Age minimum | 50years-old |
|---|---|
| Age maximum | Not applicable |
| Gender | Female |
| Include criteria | |
| Exclude criteria | 1. Patients prescribed with bisphosphonate, aluminium, lanthanum, cinacalcet. 2. Patients with venous thrombosis or its history. 3. Immobilised patients in long term. 4. Patients with anti-phospholipid antibody syndrome. 5. Patients in pregnancy (including its possibility) and lactation. 6. Patinets with history of allergy to Raloxifene. 7. Patients with liver dysfunction. |
Related Information
| Primary Sponsor | Blood Purification Center, Osaka College of Medicine |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Blood Purification Center, Osaka College of Medicine |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Katsuyuki Nagatoya |
| Address | 2-7 Takatsuki, Osaka Japan |
| Telephone | 072-683-1221 |
| katsuyuki@poh.osaka-med.ac.jp | |
| Affiliation | Osaka Medical College Blood Purification Center |
| scientific contact | |
| Name | Toru Inoue |
| Address | 2-7 Takatsuki, Osaka Japan |
| Telephone | 072-683-1221 |
| Affiliation | Osaka College of Medicine Blood Purification Center |