NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
UMIN ID: UMIN000001829

Registered date:01/04/2009

Ocular hypotensive effects of tafluprost and travoprost in normal tension glaucoma; open-label,multi center, cross-over study

Basic Information

Recruitment status
Health condition(s) or Problem(s) studiedNormal Tension Glaucoma
Date of first enrollment2009/04/01
Target sample size100
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)Tafluprost or travoprost monotherapy 12 weeks treatment once daily. Switching monotherapy from travoprost to tafluprost, or from tafluprost to travoprost 12 weeks treatment once daily

Outcome(s)

Primary OutcomeIntraocular pressure reduction, % reduction of intraocular pressure
Secondary OutcomeSafety

Key inclusion & exclusion criteria

Age minimum20years-old
Age maximumNot applicable
GenderMale and Female
Include criteria1: Patients with normal tension glaucoma 2: Untreated or over 4 weeks washout in treated with IOP-lowering medications.
Exclude criteria1: Patients with exfoliation glaucoma and neovascular glaucoma. 2: Patients with diabetic retinopathy. 3: Patients with advanced visual field loss(MD <-15dB). 4: Excessive myopia (<-6D). 5: Any corneal abnormality or other condition preventing reliable applanation tonometry. 6: Presence of any external disease and inflammation of the eye. 7: History of refractive surgery. 8: History of laser trabeculoplasty, filtering surgery, trabeculotomy, cataract surgery, and other intraocular surgery. 9: Pregnant, pregnant suspect, and nursing woman. Woman who is wishing pregnancy or is not able to prevent pregnancy. 10: The investigator declares any subject ineligible for any sound medical reason.

Related Information

Contact

public contact
Name Takanori MIzoguchi
Address 6-13 Tawara machi Sasebo city Nagasaki 857-0016 Japan
Telephone 0956-22-25681
E-mail t-mizo@siren.ocn.ne.jp
Affiliation MIzoguchi Eye Clinic Ophthalmology
scientific contact
Name Takanori MIzoguchi
Address 6-13 Tawara machi Sasebo city Ngasaki 857-0016 Japan
Telephone 0956-22-5681
E-mail
Affiliation MIzoguchi Eye Clinic Ophthalmology