UMIN ID: UMIN000001815
Registered date:30/03/2009
Prospective randomized controlled study for preventive effect of menatetrenone against the recurrence of hepatocellular carcinoma after hepatectomy
Basic Information
| Recruitment status | Complete: follow-up continuing |
|---|---|
| Health condition(s) or Problem(s) studied | Hepatocellular carcinoma |
| Date of first enrollment | 2005/11/01 |
| Target sample size | 84 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | The study was designed to test the hypothesis that MNT would reduce the incidence of recurrence of HCC in patients underwent initial hepatectomy. The patients stated to take 15 mg of menatetrenone, 3 times a day, orally everyday. Control group does not take any drugs. |
Outcome(s)
| Primary Outcome | Disease-free survival period after hepatectomy |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | Not applicable |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | Patients who take warfarin or other vitamin K analogs. |
Related Information
| Primary Sponsor | Second Department of Surgery Dokkyo Medical University |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | None. |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Tokihiko Sawada |
| Address | Kitakobayashi 880, Mibu, Shimotsuga, Tochigi Japan |
| Telephone | 0282-86-1111 |
| tsawada@dokkyomed.ac.jp | |
| Affiliation | Dokkyo Medical University Second Department of Surgery |
| scientific contact | |
| Name | Keiichi Kubota |
| Address | Kitakobayashi 880, Mibu, Shimotsuga, Tochigi Japan |
| Telephone | 0282-86-1111 |
| Affiliation | Dokkyo Medical University Second Department of Surgery |