UMIN ID: UMIN000001773
Registered date:16/03/2009
Prospective Open-labelled Randomized Controlled trial for efficacy of cholesterol lowering intervention in CKD patient with dyslipidemia
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Chronic kidney disease patient with dyslipidemia |
| Date of first enrollment | 2009/01/01 |
| Target sample size | 20 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Administration of pitavastatin 1mg. Increase up to 2mg, if LDL lowering effect of pitavastatin is insufficient Administration of ezetimibe 10mg. Pravastatin 10mg is add to ezetimibe 10mg, if LDL lowering effect of ezetimibe is insufficient |
Outcome(s)
| Primary Outcome | Urinary protein lowering effect Improvemant of GFR |
|---|---|
| Secondary Outcome | Improvement of inflammation Improvement of oxdative stress Improvement of endothelial function |
Key inclusion & exclusion criteria
| Age minimum | 18years-old |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | End stage renal disease Severe hapatic damege Hyper creatine pholphokinase Inadequate case judged by doctor |
Related Information
| Primary Sponsor | Tokyo Medical University Ibaraki Medical Center |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | None |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Homara Shimohata, Kouichi Hirayama |
| Address | 3-20-1, Amimachicyuo, Inashikigun, Ibaraki, Japan Japan |
| Telephone | 029-887-1161 |
| h-shimo@tokyo-med.ac.jp | |
| Affiliation | Tokyo Medical University Ibaraki Medical Center Department of Nephrology |
| scientific contact | |
| Name | Masaki Kobayashi |
| Address | 3-20-1, Amimachicyuo, Inashikigun, Ibaraki, Japan Japan |
| Telephone | 029-887-1161 |
| Affiliation | Tokyo Medical University Ibaraki Medical Center Department of Nephrology |