UMIN ID: UMIN000001756
Registered date:05/03/2009
Hepatitis B immunoglobulin plus Lamivudine to prevent recurrent hepatitis B following liver transplantation
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Liver transplant candidates with end-stage liver diseases due to hepatitis B. |
| Date of first enrollment | 2009/02/01 |
| Target sample size | 20 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Lamivudine |
Outcome(s)
| Primary Outcome | The rate of hepatitis B recurrence post liver-transplantation. |
|---|---|
| Secondary Outcome | To compare the rate of Hepatitis B recurrence post liver-transplantation to our histolical control (HBIG alone). |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1) HIV co-infection. 2) Lamivudine sensitivity. 3) Severe renal dysfunction (serum Cr >= 2.0 mg/dL) 4) Resistance to Lamivudine. |
Related Information
| Primary Sponsor | Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, University of Tokyo |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | None |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Noriyo Yamashiki |
| Address | 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655 Japan |
| Telephone | 03-3815-5411 |
| nyamashiki-gi@umin.ac.jp | |
| Affiliation | University of Tokyo Organ Transplantation Service |
| scientific contact | |
| Name | Yasuhiko Sugawara |
| Address | 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655 Japan |
| Telephone | 03-3815-5411 |
| Affiliation | University of Tokyo The Artificial Organ and Transplantation Division, Department of Surgery |