UMIN ID: UMIN000001732
Registered date:23/02/2009
Cancer vaccination therapy by using tumor-associated antigen GPC3-targeted peptide in the partients who have received trans-arterial infusion chemotherapy against advanced hepatocellular carcinoma -A randomized double blind study-
Basic Information
| Recruitment status | |
|---|---|
| Health condition(s) or Problem(s) studied | hepatocellular carcinoma |
| Date of first enrollment | 2009/02/01 |
| Target sample size | 20 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Cancer vaccination therapy by using tumor-associated antigen GPC3-targeted peptide in the patients who have received trans-arterial infusion chemotherapy against advanced HCCs. Cancer vaccination therapy by using IFA in the patients who have received trans-arterial infusion chemotherapy against advanced HCCs. |
Outcome(s)
| Primary Outcome | safety |
|---|---|
| Secondary Outcome | immunologicalresponse and clinical efficacy |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | 80years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1. Patients have uncontrollable associated cancer. 2. Patients have uncontrollable severe infectional diseases. 3. Patients have severe trauma. 4. Patients who are treated with steroid or immunotherapy during clinical trial. 5. Pregnancy or lactation. 6. Patients judged inappropriated by doctors. |
Related Information
| Primary Sponsor | Department of Gastroenterology and Hepatology, Graduate School of Medical Sciences Kumamoto University |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Department of Gastroenterology and Hepatology, Graduate School of Medical Sciences Kumamoto University |
| Secondary ID(s) |
Contact
| public contact | |
| Name | |
| Address | 1-1-1 Honjo, Kumamoto city, Kumamoto 860-8556, Japan Japan |
| Telephone | 096-373-5150 |
| Affiliation | Graduate School of Medical Sciences Kumamoto University Department of Gastroenterology and Hepatology |
| scientific contact | |
| Name | Yutaka Sasaki |
| Address | 1-1-1 Honjo, Kumamoto city, Kumamoto 860-8556, Japan Japan |
| Telephone | 096-373-5150 |
| Affiliation | Graduate School of Medical Sciences Kumamoto University Department of Gastroenterology and Hepatology |