UMIN ID: UMIN000001726
Registered date:22/02/2009
A randomized controlled trial of patients with obsessive-compulsive disorder: A functional magnetic resonance imaging study
Basic Information
Recruitment status | Complete: follow-up complete |
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Health condition(s) or Problem(s) studied | obsessive-compulsive disorder(OCD) |
Date of first enrollment | 2001/08/01 |
Target sample size | 45 |
Countries of recruitment | Japan |
Study type | Interventional |
Intervention(s) | Fluvoxamine, up to a dose of 200mg/day, Autogenic Training (a psychological placebo), once a week for 12 weeks pill placebo behavior therapy, once a week for 12 weeks pill placebo Autogenic Training (a psychological placebo), once a week for 12 weeks |
Outcome(s)
Primary Outcome | Yale-Brown Obsessive Compulsive Scale (Y-BOCS) (after the 12-week treatment) functional activation maps (before and after treatment) Neuropsychological tests (attention, executive function, memory) |
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Secondary Outcome | Hamilton Depressive Rating Scale (HDRS) State-Trait Anxiety Inventory (STAI) (after the 12-week treatment) |
Key inclusion & exclusion criteria
Age minimum | 18years-old |
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Age maximum | 60years-old |
Gender | Male and Female |
Include criteria | |
Exclude criteria | comorbid axis I diagnosis neurological disorder head injury serious medical condition history of drug/alcohol addiction a total y-BOCS score lower than 16 a HDRS score more than 18 points a total IQ of less than 80 |
Related Information
Primary Sponsor | Kyushu University |
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Secondary Sponsor | |
Source(s) of Monetary Support | the Japanese Ministry of Education, Culture, Sports, Science and Technology |
Secondary ID(s) |
Contact
public contact | |
Name | Tomohiro Nakao |
Address | 3-1-1 Maidashi Higashi-ku, Fukuoka, Japan Japan |
Telephone | |
Affiliation | Graduate School of Medical Sciences, Kyushu University Department of Neuropsychiatry |
scientific contact | |
Name | Shigenobu Kanba |
Address | 3-1-1 Maidashi Higashi-ku, Fukuoka, Japan Japan |
Telephone | |
Affiliation | Graduate School of Medical Sciences, Kyushu University Department of Neuropsychiatry |