NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
UMIN ID: UMIN000001726

Registered date:22/02/2009

A randomized controlled trial of patients with obsessive-compulsive disorder: A functional magnetic resonance imaging study

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedobsessive-compulsive disorder(OCD)
Date of first enrollment2001/08/01
Target sample size45
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)Fluvoxamine, up to a dose of 200mg/day, Autogenic Training (a psychological placebo), once a week for 12 weeks pill placebo behavior therapy, once a week for 12 weeks pill placebo Autogenic Training (a psychological placebo), once a week for 12 weeks

Outcome(s)

Primary OutcomeYale-Brown Obsessive Compulsive Scale (Y-BOCS) (after the 12-week treatment) functional activation maps (before and after treatment) Neuropsychological tests (attention, executive function, memory)
Secondary OutcomeHamilton Depressive Rating Scale (HDRS) State-Trait Anxiety Inventory (STAI) (after the 12-week treatment)

Key inclusion & exclusion criteria

Age minimum18years-old
Age maximum60years-old
GenderMale and Female
Include criteria
Exclude criteriacomorbid axis I diagnosis neurological disorder head injury serious medical condition history of drug/alcohol addiction a total y-BOCS score lower than 16 a HDRS score more than 18 points a total IQ of less than 80

Related Information

Contact

public contact
Name Tomohiro Nakao
Address 3-1-1 Maidashi Higashi-ku, Fukuoka, Japan Japan
Telephone
E-mail
Affiliation Graduate School of Medical Sciences, Kyushu University Department of Neuropsychiatry
scientific contact
Name Shigenobu Kanba
Address 3-1-1 Maidashi Higashi-ku, Fukuoka, Japan Japan
Telephone
E-mail
Affiliation Graduate School of Medical Sciences, Kyushu University Department of Neuropsychiatry