NIPH Clinical Trials Search

UMIN ID: UMIN000001720

Registered date:23/02/2009

Evaluation of the effect of Angiotensin ll receptor blocker for plaque vulnerability after percutaneous coronary intervention (PCI)

Basic Information

Recruitment status
Health condition(s) or Problem(s) studiedHypertension with coronary artery disease
Date of first enrollment2009/02/01
Target sample size40
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)Telmisartan + Pravastatin sodium Antiypertensive agents except RAS blocker + Pravastatin sodium


Primary OutcomeChange in plaque composition and observation by Integrated Backscatter Intravascular Ultrasound (IB-IVUS)
Secondary Outcome1) Change in surrogate marker in coronary vein blood hs-CRP,IL-6,TNF-alpha,IP-10,MMP-3, MMP-9,MCP-1,MIF,PTX-3,Heparin cofactor 2) Office blood pressure

Key inclusion & exclusion criteria

Age minimum20years-old
Age maximum80years-old
GenderMale and Female
Include criteria
Exclude criteria1) Previous storoke<=6month 2) Ejection fraction<=40% 3) Patients with dialysis 4) Diabetic patients with HbA1c<=6.5 5) Patients who are treated with statin except pravastatin sodium

Related Information


public contact
Address Japan
Telephone 088-633-7852
Affiliation The University of Tokushima Institute of Health Biosciences Graduate School Cardiovascular Medicine
scientific contact
Name Masataka SATA
Address 3-18-15 Kuramoto-Cho Tokushima Japan
Affiliation The University of Tokushima Cardiovascular Medicine