UMIN ID: UMIN000001719
Registered date:23/02/2009
Tokushima Anti-Oxidation Clinical Trial In hypertensives, Cilnidipine versus Amlodipine
Basic Information
| Recruitment status | |
|---|---|
| Health condition(s) or Problem(s) studied | hypertension |
| Date of first enrollment | 2009/02/01 |
| Target sample size | 50 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | clinidipine (initial dose is 10mg/day, but 10-20mg is available depending on the blood pressure level) amlodipine (initial dose is 5mg/day, but 5-10mg is available depending on the blood pressure level) |
Outcome(s)
| Primary Outcome | 1.Clinic blood pressure,heart rate. 2.Home blood pressure,heart rate. 3.urinary 8-OHdG. 4.hs-CRP 5.urinary albumin-creatinine ratio. 6.urinary L-FABP. 7.LDL-C,TG,HDL-C,BUN,Cr,*HbA1c*fasting blood glucose(*Patients with diabetes) |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | 45years-old |
|---|---|
| Age maximum | 75years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1.Malignant hypertension 2.Pregnant women,or Women suspected of being pregnant. 3.Severe liver disorder. 4.Patients who are inadequate to enter this study due to the other reasons by physician's judgments. |
Related Information
| Primary Sponsor | Cardiovascular Medicine, The University of Tokushima Institute of Health Biosciences, Graduate School |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | None |
| Secondary ID(s) |
Contact
| public contact | |
| Name | |
| Address | Japan |
| Telephone | 088-633-7852 |
| Affiliation | The University of Tokushima Institute of Health Biosciences, Graduate School Cardiovascular Medicine |
| scientific contact | |
| Name | Masataka SATA |
| Address | 3-18-15 Kuramoto-cho,Tokushima Japan |
| Telephone | |
| Affiliation | The University of Tokushima Institute of Health Biosciences, Graduate School Cardiovascular Medicine |