UMIN ID: UMIN000001678
Registered date:02/02/2009
Preventive effect of rabeprazole and sucralfate on gastroduodenal mucosal injury in patients taking low-dose aspirin
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Patients who have plan to receive low-dose aspirin |
| Date of first enrollment | 2009/02/01 |
| Target sample size | 60 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | rabeprazole: 10mg/day, 4 week given with aspirin 100mg/day scralfate 3g/day, 4 week given with aspirin 100mg/day |
Outcome(s)
| Primary Outcome | Change of endoscopic finding before and 4 weeks after initiating low-dose aspirin (Comparison between rabeprazole and sucralfate) |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1.taking low-dose aspirin 2.below 20 years of age 3.contraindication against rabeprazole and sucralfate 4.malignancy 5.pregnancy |
Related Information
| Primary Sponsor | Department of Internal Medicine, Teikyo University School of Medicine |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Teikyo University School of Medicine |
| Secondary ID(s) |
Contact
| public contact | |
| Name | |
| Address | Japan |
| Telephone | |
| ymmt@med.teikyo-u.ac.jp | |
| Affiliation | Teikyo University School of Medicine Internal Medicine |
| scientific contact | |
| Name | Yasushi Kuyama |
| Address | 2-11-1 Kaga Itabashiku Tokyo Japan |
| Telephone | 03-3964-1211 |
| Affiliation | Teikyo University School of Medicine Internal Medicine |