UMIN ID: UMIN000001673
Registered date:30/01/2009
Role of food intolerance and effect of protease inhibitor in patients with irritable bowel syndrome (IBS)
Basic Information
| Recruitment status | Complete: follow-up continuing |
|---|---|
| Health condition(s) or Problem(s) studied | Irritable bowel syndrome (IBS) |
| Date of first enrollment | 2009/02/01 |
| Target sample size | 30 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Camostat mesilate 200mg (t.i.d.) will be administrated for 14 days. Rectal barostat measurements will be performed before and the end of the intervention. Placebo (t.i.d.) will be administrated for 14 days. Rectal barostat measurements will be performed before and the end of the intervention. |
Outcome(s)
| Primary Outcome | Adequate relief (AR) at the end of the intervention |
|---|---|
| Secondary Outcome | Symptom severity at the end of the intervention |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | Patients who have severe systemic/ psychological complications, and/or who have histories of any abdominal surgery except appendectomy, and/or who needs to continue any pharmacological treatment during the study |
Related Information
| Primary Sponsor | Tohoku University Graduate School of Medicine |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Grant-in-Aid for Scientific Research from the Ministry of Education, Science and Culture of Japan |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Motoyori Kanazawa, MD, PhD |
| Address | Japan |
| Telephone | |
| Affiliation | Tohoku University Graduate School of Medicine Department of Behavioral Medicine |
| scientific contact | |
| Name | Shin Fukudo, MD, PhD |
| Address | 2-1 Seiryo, Aoba, Sendai 980-8575, Japan Japan |
| Telephone | |
| Affiliation | Tohoku University Graduate School of Medicine Department of Behavioral Medicine |