NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
UMIN ID: UMIN000001652

Registered date:23/01/2009

A randomized controlled trial for low-dose continuous Infusion of human atrial natriuretic peptide for cardiac dysfunction undergoing cardiac surgery

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedmyocardial infarction, angina
Date of first enrollment1997/03/01
Target sample size130
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)Perioperative administration of hANP Perioperative non-administration of hANP

Outcome(s)

Primary OutcomeEarly postoperative outcome(mortality and complications) Long-term results(cardiac death-and events-free rate, overall survival rate after surgery))
Secondary Outcomecardiac function(UCG, BNP) renal function (sCr,eGFR,Maximum sCr,Increase of Cr,(pre-max. sCr) > 0.3 mg/dl) ANP, renin, anigotensin-II, aldsterone

Key inclusion & exclusion criteria

Age minimum20years-old
Age maximum90years-old
GenderMale and Female
Include criteria
Exclude criteriacardiogenic shock renal dysfunction with hemodyalysis

Related Information

Contact

public contact
Name Akira Sezai
Address 30-1 Oyagichi kami-machi, Itabashi-ku, Tokyo Japan
Telephone 03-3972-8111
E-mail asezai.med@gmail.com
Affiliation Nihon University School of Medicine Department of Cardiovascular Surgery
scientific contact
Name Akira Sezai
Address 30-1 Oyaguchi kami-machi, Itabashi-ku, Tokyo, Japan Japan
Telephone 03-3972-8111
E-mail asezai.med@gmail.com
Affiliation Nihon University School of Medicine Department of Cardiovascular Surgery