UMIN ID: UMIN000001643
Registered date:19/01/2009
Trial of Proteinuria Reduction Effect of Losartan/Hydrochlorothiazide Therapy to Chronic Kidney Disease with Hypertension
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Chronic kidney disease patients with hypertension |
| Date of first enrollment | 2009/01/01 |
| Target sample size | 120 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | ARB/hydrochlorothiazide combination drug ARB |
Outcome(s)
| Primary Outcome | The primary end point is change in the Up:Ucr ratio from baseline to month 12. |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | 75years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | Patients with uncontrolled hypertension, serum patassium >5.5 mEq/L, cardiovascular disease (myocardial infarction, unstable angina, stroke within last 3 months), pregnancy,lactation,nephrotic syndrome (serum Alb <2g/dl), frequent users of diuretics are excluded. |
Related Information
| Primary Sponsor | Kyushu University Hospital Kidney Care Unit |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | no fundation |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Kiichiro Fujisaki |
| Address | 3-1-1 Maidashi, higashi-ku Fukuoka Japan |
| Telephone | 092-642-5843 |
| Affiliation | Kyushu University Hospital Kidney Care Unit |
| scientific contact | |
| Name | Kazuhiko Tsuruya |
| Address | 3-1-1 Maidashi, higashi-ku Fukuoka Japan |
| Telephone | 092-642-5843 |
| Affiliation | Kyushu University Department of integrated therapy for chronic kidney disease graduate school of medical sciences |