UMIN ID: UMIN000001616
Registered date:03/01/2009
Antiproteinuric and blood pressure-lowering effects of fixed combinations of ARB / hydrochlorothiazide in hypertensive patients with chronic kidney disease
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Chronic kidney disease |
| Date of first enrollment | 2008/10/01 |
| Target sample size | 50 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | losartan/HCTZ fixed combination |
Outcome(s)
| Primary Outcome | Blood pressure lowering effect, Change of the urinary protein excretion, Change of the renal function, adverse effects |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | 80years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1) Age < 20 or over 80 y/o 2) CKD stage 4-5 3) hypertensive emergency 4) Severe diabetes mellitus 5) Renovascular or endocrine hypertension |
Related Information
| Primary Sponsor | Division of Nephrology, Hypertension and Endocrinology, Nihon University School of Medicine |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | None |
| Secondary ID(s) |
Contact
| public contact | |
| Name | |
| Address | Japan |
| Telephone | |
| mabe@med.nihon-u.ac.jp | |
| Affiliation | Nihon University Nerima Hikarigaoka Hospital Internal medicine |
| scientific contact | |
| Name | Masanori Abe |
| Address | 30-1, Oyaguchikamimachi, Itabashi-ku, Tokyo, Japan Japan |
| Telephone | |
| Affiliation | Nihon University School of Medicine Nephrology, Hypertension and Endocrinology |