NIPH Clinical Trials Search

UMIN ID: UMIN000001608

Registered date:05/01/2009

Establishment of surveillance system for the longstanding ulcerative colitis patients Comparative study of efficacy for the targeted biopsy and the step biopsy

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedUlcerative colitis
Date of first enrollment2009/01/01
Target sample size200
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)Targeted biopsy Step biopsy


Primary OutcomeThe number of neoplastic lesions detected during surveillance colonoscopy
Secondary OutcomeThe detection rate of neoplastic lesions, examination time and a number of biopsies in the surveillance colonoscopy (economical efficiency, incidence rate of complication that requires the special treatment, risk factor of neoplasia)

Key inclusion & exclusion criteria

Age minimumNot applicable
Age maximumNot applicable
GenderMale and Female
Include criteria
Exclude criteria1)Patients who have past history of colon cancer and/or ulcerative colitis associated neoplasm 2) Patients suspected of bleeding diathesis or coagulation abnormality 3) Renal dysfunction (Cre > 1.2 mg/dl) 4)Pregnancy or breast feeding 5)Otherwise, patiesnts who investigator judged ineligible to register

Related Information


public contact
Name Naoki Tomotsugu
Address 35 Shinanomachi Shinjuku Tokyo Japan
Telephone 03-5363-3288
Affiliation Keio University School of Medicine Center for Clinical Research
scientific contact
Name Toshiaki Watanabe, M.D., Ph.D.
Address 2-11-1 Kaga Itabashiku Tokyo Japan
Telephone 03-3964-1231
Affiliation Teikyo University School of Medicine Surgery