UMIN ID: UMIN000001598
Registered date:05/01/2009
Effect of ghrelin on airway inflammation in patients with chronic lower respiratory infection
Basic Information
| Recruitment status | |
|---|---|
| Health condition(s) or Problem(s) studied | chronic lower respiratory infection |
| Date of first enrollment | 2009/01/01 |
| Target sample size | 40 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Human ghrelin (2microgram/kg, 20 mL solution) was intravenously administered to the patients for 30 min at a constant rate before breakfast and dinner for 2 weeks continuously. After one week interval, the same volume of salin was intravenously administered to the patients for 30 min at a constant rate before breakfast and dinner for 2 weeks continuously. Twenty ml of salin was intravenously administered to the patients for 30 min at a constant rate before breakfast and dinner for 2 weeks continuously. After one week interval, human ghrelin (2microgram/kg, 20 mL solution) was intravenously administered to the patients for 30 min at a constant rate before breakfast and dinner for 2 weeks continuously. |
Outcome(s)
| Primary Outcome | volume of sputum |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | Not applicable |
|---|---|
| Age maximum | 80years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1) patients with diabetes mellitus, severe cardiac disease, hepatic disease, renal insufficiency 2) pregnant women 3) patients with infections in other organs than the lungs |
Related Information
| Primary Sponsor | Miyazaki University School of Medicine |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Ministry of Health, Labour and Welfare |
| Secondary ID(s) |
Contact
| public contact | |
| Name | |
| Address | Japan |
| Telephone | |
| Affiliation | Miyazaki University School of Medicine Third Department of Internal Medicine |
| scientific contact | |
| Name | Nakazato Masamitsu |
| Address | Kihara 5200, kiyotake, Miyazaki Japan |
| Telephone | |
| Affiliation | Miyazaki University School of Medicine Third Department of Internal Medicine |