NIPH Clinical Trials Search

UMIN ID: UMIN000001584

Registered date:17/12/2008

A Phase II study of neoadjuvant chemotherapy with S-1 and cisplatin for Stage III gastric cancer

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedStage III gastric cancer
Date of first enrollment2008/12/01
Target sample size49
Countries of recruitmentJapan
Study typeInterventional


Primary Outcome3 year progression free survival rate
Secondary Outcome

Key inclusion & exclusion criteria

Age minimum20years-old
Age maximum80years-old
GenderMale and Female
Include criteria
Exclude criteria1)Active bleeding from the tumor 2)Paralysis of intestine or ileus 3)Diarrhea(watery stool) 4)Patient who requires continuous use of flucytosine, phenytoin or warfarin potassium 5)Synchronous multicancer 6)Serous infection 7)Interstitial pneumonitis or fibroid lung 8)Pleural effusion or ascites requiring control 9)Uncontrollable diabetes mellitus, uncontrollable hypertention, heart insufficiency, myocardial infarction within 6 months,uncontrolled arrhythmia or angina 10)Patient who is pregnant or in lactation, or wish to become pregnant during this study.Male patient who intends to make someone pregnant during this study 11)Patient who has experienced serious drug allergy in the past 12)Patient with severe phyciatric disease 13)Patient who is judged to be inappropriate as subject to this study by the principal investigator or the doctors in charge

Related Information


public contact
Address Japan
Telephone 075-751-3227
Affiliation Graduate School of Medicine, Kyoto University Department of Surgery
scientific contact
Name Yoshiharu SAKAI
Address 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, JAPAN Japan
Affiliation Graduate School of Medicine, Kyoto University Department of Surgery