UMIN ID: UMIN000001578
Registered date:16/12/2008
Tyrosine Kinase Inhibitor for the Treatment of Severe Pulmonary Arterial Hypertension
Basic Information
| Recruitment status | |
|---|---|
| Health condition(s) or Problem(s) studied | pulmonary arterial hypertension |
| Date of first enrollment | 2008/12/01 |
| Target sample size | 10 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | administration of tyrosine kinase inhibitor (imatinib) |
Outcome(s)
| Primary Outcome | subjective symptom (WHO functional classification), 6 minutes walk test, echocardiography, right heart catheterization, serum BNP level |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | patients who can not express subjective symptoms, can not be evaluated through objective improvement, have the decreased number of platelet (less than 30000), have critical anemia (Hb<7.0), have critical liver cirrhosis, are during pregnancy or during lactation, or have critical left heart disease |
Related Information
| Primary Sponsor | Medical Education Center |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | none |
| Secondary ID(s) |
Contact
| public contact | |
| Name | |
| Address | 35 Shinanomachi, Shinjuku-ku, Tokyo Japan |
| Telephone | |
| Affiliation | School of Medicine, Keio University Medical Education Center |
| scientific contact | |
| Name | Toru Satoh |
| Address | 35 Shinanomachi, Shinjuku-ku, Tokyo Japan |
| Telephone | |
| Affiliation | School of Medicine, Keio University Medical Education Center |