NIPH Clinical Trials Search

UMIN ID: UMIN000001541

Registered date:01/01/2009

Phase II trial of combination chemotherapy consisting of S-1 and Oxaliplatin in patients with advanced or recurrent mucinous adenocarcinoma of the ovary

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedMucinous adenocarcinoma of the ovary including metastatic ovarian cancer
Date of first enrollment2008/08/01
Target sample size40
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)Combination chemotherapy consisting of S-1+ Oxaliplatin (SOX)


Primary OutcomeResponse rate
Secondary OutcomeThe incidence of adverse event Progression free survival Overall survival

Key inclusion & exclusion criteria

Age minimum20years-old
Age maximumNot applicable
Include criteria
Exclude criteria1.Patients having fever over 38.0 2.Patients with infection or more than WBC:12,000/mm3 3.Patients with severe complications 4.Patients with double cancer 5.Patients with massive pleural effusion, ascites and pericardial fluid need to continuous drainage 6.Patients with severe paresthesia with functional disorder, or dysesthesia 7.Patients who cannot undergo treatment due to the past history of mental disorder or the central nerve disorder 8.Patients with brain metastasis 9.Patients with more than grade 3 diarrhea. More than grade 2 diarrhea in patients receiving colostomy.

Related Information


public contact
Name Muneaki Shimada
Address Nishimachi 36-1, Yonago, Japan Japan
Telephone 0859-38-6647
Affiliation Faculty of Medicine, Tottori University Department of Obstetrics and Gynecology
scientific contact
Name Junzo Kigawa
Address Nishimachi 36-1, Yonago, Japan Japan
Telephone 0859-38-6292
Affiliation Tottori University Hospital Cancer Center