NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
UMIN ID: UMIN000001512

Registered date:01/12/2008

Clinical trial with ghrelin for patients with chronic respiratory failure

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiedchronic respiratory failure
Date of first enrollment2008/12/01
Target sample size50
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)Human ghrelin (1 microgram/kg, 10 mL solution) was intravenously administered to the patients for 30 min at a constant rate before breakfast and dinner for 3 weeks continuously. Human ghrelin (2 microgram/kg, 10 mL solution) was intravenously administered to the patients for 30 min at a constant rate before breakfast and dinner for 3 weeks continuously.

Outcome(s)

Primary Outcome6-min walking distance
Secondary Outcome

Key inclusion & exclusion criteria

Age minimumNot applicable
Age maximum80years-old
GenderMale and Female
Include criteria
Exclude criteria1)patient with cancer (and/or post-operative state), lymphangiomyomatosis, lymphoproliferative disease, collagen lung, neuromuscular disease, primary hypoventilation syndrome, pneumoconiosis, eosinophilic granulomatosis, and/or diffuse panbronchiolitis 2)patient with diabetes mellitus (HbA1c>8.0) 3)patient with severe heart disease 4)patient with liver dysfunction 5)patient with renal dysfunction 6)pregnant woman 7)patient with dementia

Related Information

Contact

public contact
Name
Address Kihara 5200, Kiyotake, Miyazaki Japan
Telephone
E-mail
Affiliation Miyazaki University school of Medicine Third Department of Internal Medicine
scientific contact
Name Nakazato Masamitsu
Address Kihara 5200, Kiyotake, Miyazaki Japan
Telephone
E-mail
Affiliation Miyazaki University school of Medicine Third Department of Internal Medicine