UMIN ID: UMIN000001456
Registered date:01/04/2010
The effect of angiotensin II receptor blocker (ARB) or thiazolidinedione (TZD) on adipocytokines and oxidative stress markers (Senri Study II)
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Hypertensive and/or Diabetic patients |
| Date of first enrollment | 2008/08/01 |
| Target sample size | 200 |
| Countries of recruitment | Japan |
| Study type | Observational |
| Intervention(s) |
Outcome(s)
| Primary Outcome | Changes of TBARS(Thiobarbituric acid reactive substances), highsensitive CRP, and Adiponectin at the completion of treatment form baseline |
|---|---|
| Secondary Outcome | Changes of waist circumference, glucose-lipid metabolic parameters, and blood pressure |
Key inclusion & exclusion criteria
| Age minimum | Not applicable |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1)Contraindications of candesartan 2)Contraindications of Pioglitazone |
Related Information
| Primary Sponsor | Department of Metabolic Medicine, Graduate School of Medicine, Osaka University |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Department of Metabolic Medicine, Graduate School of Medicine, Osaka University |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Ken Kishida |
| Address | Japan |
| Telephone | |
| kkishida@imed2.med.osaka-u.ac.jp | |
| Affiliation | Osaka University Metabolic medicine |
| scientific contact | |
| Name | Iichiro Shimomura, Tohru Funahashi |
| Address | 2-2 B5, Yamada-oka, Suita, Osaka, 565-0871, Japan Japan |
| Telephone | 06-6879-3732 |
| Affiliation | Osaka University Metabolic medicine |