UMIN ID: UMIN000001399
Registered date:27/09/2008
Analysis of the symptom of gastro-esophageal reflux after H. pylori eradication
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Patients with H. pylori-positive peptic ulcer disease, who are planned to eradicate H. pylori. |
| Date of first enrollment | 2008/09/01 |
| Target sample size | 200 |
| Countries of recruitment | Japan |
| Study type | Observational |
| Intervention(s) |
Outcome(s)
| Primary Outcome | Gastro-esophageal reflux score (QUEST), QOL score (QOLRAD-J) at 0, 1, 12, 24, 48 weeks after the H. pylori eradication |
|---|---|
| Secondary Outcome | Pepsinogen I, pepsinogen II at 0, 3, 6 and 12 months after the H. pylori eradication |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | 70years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1. Hypersensitivity to omeprazole 2. patients taking atazanavir sulfate 3. Patients with severe liver dysfunction or renal dysfunction 4. Expectant mother 5. patients having taken PPIs 6. patients who is decided as not suitable to this study by doctors |
Related Information
| Primary Sponsor | Keio University School of Medicine |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Astra-Zeneca |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Hidekazu Suzuki |
| Address | 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan Japan |
| Telephone | 03-5363-3914 |
| hsuzuki.a6@keio.jp | |
| Affiliation | Keio University School of Medicine Medical Education Center |
| scientific contact | |
| Name | Hidekazu Suzuki, M.D., Ph.D. |
| Address | 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan Japan |
| Telephone | 03-5363-3914 |
| hsuzuki.a6@keio.jp | |
| Affiliation | Keio University School of Medicine Medical Education Center |