Clinical study of Prevention and Actual situation of Venous Thromboembolism after Total Arthroplasty

UMIN ID: UMIN000001366

Registered date:11/09/2008

Basic Information

• Health condition(s) or Problem(s) studied: Venous Thromboembolism Osteoarthrosis
• Date of first enrollment: 2008/07/01
• Target sample size: 1400
• Countries of recruitment: Japan
• Study type: Observational

Outcome(s)

• Primary Outcome: The DVT that was confirmed by sonography of Day10(No symptom characteristics). DVT/PE symptom that broke out by Day25.

Key inclusion & exclusion criteria

• Age minimum: 20years-old
• Age maximum: Not applicable
• Gender: Male and Female
• Exclude criteria: 1.A patient with the past of the blood dyscrasia(a ProteinC,S,AT-3 deficiency disease,an antiphosphatide antibody syndrome,hemophilia)with the solldification abnormality. 2.A atient having tha hemorrhagic mental change caused by a disease(tha hemorrhagic mental changes caused by a disease of the important internalorgans such as a digestive ulcer,the bleeding in the skull). 3.Heart failure(NYHA classification ciass 3 or 4) 4.Renal insufficiency(less than 30ml/min creatinine clearance) 5.Liver function disorder(more than AST institution standard upper limit 5 times or more than 3 times of the ALT upper limit and total bilirubin,more than 2 times of the upper limit). 6.The patient who plan to have simultaneous Total joint anthroplasty for both side. 7.The patient that Total joint arthroplasty was enforced within the past three months,or revisit. 8.The patient whom the chief physician recognizes as inappropriateness for this study participation. 9.The patient who tries artificial feeding(tubal feeding,central vein nourishment). 10.The patient who is not able to walk.

Related Information

• Primary Sponsor: National Hospital Organization
• Source(s) of Monetary Support: National Hospital Organization