UMIN ID: UMIN000001362
Registered date:01/10/2008
Clinical effect of luekotriene receptor antagonist on provocation symptom induced by Japanese cedar pollene antigen disc and grope for clinical marker of nasal obstraction
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Japanese cedar pollinosis |
| Date of first enrollment | 2008/09/01 |
| Target sample size | 60 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | It is given the test capsule containing leukotriene receptor antagonist(montelukast Na 10mg): 1 capsule per 1 day for a week before the Japanese cedar pollene provocation test. It is given the placebo capsule containing lactatose powder: 1 capsule per 1 day for a week before the Japanese cedar pollene provocation test. |
Outcome(s)
| Primary Outcome | Effect of leukotriene receptor antagonist |
|---|---|
| Secondary Outcome | Serum and urinary oxidized stress substances concentration. Nicotid Oxide concentration in nasal cavity |
Key inclusion & exclusion criteria
| Age minimum | 18years-old |
|---|---|
| Age maximum | 60years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | Pregnancy, potential pregnancy, and breast-feeding patient. |
Related Information
| Primary Sponsor | Faculity of Medicine, University of Fukui |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Dep. of Otorhinolaryngology-Head and Neck Surgery, Faculity of Medicine, University of Fukui |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Youko Osawa |
| Address | 23 Matsuokashimoaiduki, Eiheiji-Cho, Yoshida-gun, Fukui Prefecture Japan |
| Telephone | 0776-61-3111(ext.2398) |
| fukuoka@u-fukui.ac.jp | |
| Affiliation | Faculity of Medicine, University of Fukui Dep. of Otorhinolaryngology-Head and Neck Surgery |
| scientific contact | |
| Name | Shigeharu Fujieda |
| Address | 23 Matsuokashimoaiduki, Eiheiji-Cho, Yoshida-gun, Fukui Prefecture Japan |
| Telephone | 0776-61-3111(ext.2398) |
| Affiliation | Faculity of Medicine, University of Fukui Dep. of Otorhinolaryngology-Head and Neck Surgery |