UMIN ID: UMIN000001316
Registered date:20/08/2008
Multicenter randomized trial of the prevention of gastric mucosal injury with Rabeprazol in chemotherapeutic cases of pancreatic cancer
Basic Information
| Recruitment status | |
|---|---|
| Health condition(s) or Problem(s) studied | Pancreatic Cancer |
| Date of first enrollment | 2007/07/01 |
| Target sample size | 60 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | A:Rabeprazole(10mg/Day)adiminisitration between 8weeks B:Without administration of any kind of PPI or H2RA |
Outcome(s)
| Primary Outcome | Modified Lanza score |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1 Patients with gastric ulcer or esophagial varices 2 Lanza score, greater or equal 2 3 Direct invasion to gastric or duodenal mucosa 4 Patients who have the symptom of abdominal pain or heartburn 5 Patients who take NSAIDs or steroids 6 Patients who had taken PPI or H2RA within 14 days before start of chemothrapy 7 Patients who had liver chirrosis 8 Patients who ware given gastric resection 9 Performance status, greater or equal 3 10 Patients who had undertaken adverse event caused by PPI 11 Patients who were determined inadequate by doctor |
Related Information
| Primary Sponsor | Faculty of Mediceine, University of Tokyo |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | nothing |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Yoko Yashima |
| Address | 7-3-1,Hongo,Bunkyo-ku,Tokyo Japan |
| Telephone | |
| Affiliation | Tokyo University Hospital Department of gastroenterology |
| scientific contact | |
| Name | Hiroyuki Isayama |
| Address | 7-3-1,Hongo,Bunkyo-ku,Tokyo Japan |
| Telephone | |
| Affiliation | Tokyo University Hospital Department of gastroenterology |