UMIN ID: UMIN000001287
Registered date:04/08/2008
Prevention of dialysate-induced peritoneal damage by pyridoxal phosphate
Basic Information
| Recruitment status | |
|---|---|
| Health condition(s) or Problem(s) studied | Patients with end-stage renal disease on peritoneal dialysis |
| Date of first enrollment | 2009/03/01 |
| Target sample size | 40 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Group I; Patients treated with glucose-based dialysate, to whom PLP is not given (n=20). Group II; Patients treated with glucose-based dialysate, to whom PLP is given (300mg/day, n=20) |
Outcome(s)
| Primary Outcome | After starting PLP treatment, the concentrations of growth factors, chemical mediators and AGE in used dialysate will be regularly measured and those indices will be compared between dialysate before and after PLP treatment. |
|---|---|
| Secondary Outcome | An appropriate daily dosage of PLP will be determined. |
Key inclusion & exclusion criteria
| Age minimum | 18years-old |
|---|---|
| Age maximum | 80years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1, Patients with heart failure of NYHAIII and IV |
Related Information
| Primary Sponsor | Miyanomori Memorial Hospital |
|---|---|
| Secondary Sponsor | Nikko Memorial Hospital |
| Source(s) of Monetary Support | Miyanomori Memorial Hospital |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Sakurako Nakamura |
| Address | 3-7-5-25 Miyanomori, Chuou-ku, Sapporo 064-8570, Japan Japan |
| Telephone | 011-641-6641 |
| s.nakamura@miyanomori.or.jp | |
| Affiliation | Miyanomori Memorial Hospital Clinical nephrology |
| scientific contact | |
| Name | Sakurako Nakamura |
| Address | 3-7-5-25 Miyanomori, Chuou-ku, Sapporo 064-8570, Japan Japan |
| Telephone | 011-641-6641 |
| Affiliation | Miyanomori Memorial Hospital Clinical nephrology |