UMIN ID: UMIN000001281
Registered date:31/07/2008
Strategic reduction of joint destruction in rheumatoid arthritis
Basic Information
| Recruitment status | |
|---|---|
| Health condition(s) or Problem(s) studied | Rheumatoid arthritis |
| Date of first enrollment | 2008/07/01 |
| Target sample size | 120 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | TNF-inhibitors plus MTX TNF-inhibitors are used for 54 weeks and exchange among them is approved MTX MTX is used for 54 weeks and addition of the other DMARD is approved |
Outcome(s)
| Primary Outcome | Comparison of reduction of joint destruction between TNF-inhibitors and MTX alone. |
|---|---|
| Secondary Outcome | (1) new bone erosion (2) DAS28 (3) EULAR-improvement criteria (4) HAQ |
Key inclusion & exclusion criteria
| Age minimum | Not applicable |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | Patients who met the following criteria are excluded. 1. patients with contra-indication to MTX 2. patients with contra-indication to TNF-inhibitors 3. patients who are not appropriate to the study by a doctor's judgement |
Related Information
| Primary Sponsor | School of Medicine, University of Occupational and Environmental Health, Japan |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | a Research Grant-In-Aid for Scientific Research from the Ministry of Health, Labor and Welfare of Japan |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Kazuyoshi Saito |
| Address | 1-1, Iseigaoka, Yahata-nishi-ku, Kitakyushu, 807-8555, Japan Japan |
| Telephone | 093-603-1611 |
| Affiliation | School of Medicine, University of Occupational and Environmental Health, Japan First Department of Internal Medicine |
| scientific contact | |
| Name | Yoshiya Tanaka |
| Address | 1-1, Iseigaoka, Yahata-nishi-ku, Kitakyushu, 807-8555, Japan Japan |
| Telephone | 093-603-1611 |
| Affiliation | School of Medicine, University of Occupational and Environmental Health, Japan First Department of Internal Medicine |