NIPH Clinical Trials Search

UMIN ID: UMIN000001230

Registered date:02/07/2008

Secondary Prevention of Cerebral Infarction Epidemiological Study on Cerebral Microbleeds

Basic Information

Recruitment status
Health condition(s) or Problem(s) studiedcerebral infaction
Date of first enrollment2008/07/01
Target sample size4000
Countries of recruitmentJapan
Study typeObservational


Primary Outcomesymptomatic cerebral infarction and symptomatic cerebral hemorrhage
Secondary Outcomenumber of cerebral microbleeds, Grade of DWMH and PVH, ADL, event by antiplatelet drugs, symptom of upper GI and QOL, other cerebrovascular event, cardiovascular event, death

Key inclusion & exclusion criteria

Age minimum40years-old
Age maximum85years-old
GenderMale and Female
Include criteria
Exclude criteriarecurred symptomatic cerebral infarction medicatin of antiplatelet drugs before onset moyamoya disease, AVM, AN, dural AVF previous cerebral contusion previous craniotomy and/or burr hole surgery future surgery and/or intervention for brain and heart previous symptomatic cerebral hemorrhage, other hemorrhagic disease, coagulopathy present malignancy platelet count<10000/m3 liver dysfunction (AST>100IU/L, ALT>100IU/L) renal dysfunction (Cre>3mg/dl) future moving, diffculties for follow-up amyloid angiopathy participants in other intervening clinical research

Related Information


public contact
Address Japan
Affiliation SCIENCE Study Group SCIENCE Study office
scientific contact
Name Nobuo Hashimoto
Address 5-7-1 Fujishiro-dai, Suita, Osaka 565-8565 Japan
Affiliation Graduate School of Medicine Kyoto University (present National Cardiovascular Center) Department of Neurosurgery