UMIN ID: UMIN000001230
Registered date:02/07/2008
Secondary Prevention of Cerebral Infarction Epidemiological Study on Cerebral Microbleeds
Basic Information
| Recruitment status | |
|---|---|
| Health condition(s) or Problem(s) studied | cerebral infaction |
| Date of first enrollment | 2008/07/01 |
| Target sample size | 4000 |
| Countries of recruitment | Japan |
| Study type | Observational |
| Intervention(s) |
Outcome(s)
| Primary Outcome | symptomatic cerebral infarction and symptomatic cerebral hemorrhage |
|---|---|
| Secondary Outcome | number of cerebral microbleeds, Grade of DWMH and PVH, ADL, event by antiplatelet drugs, symptom of upper GI and QOL, other cerebrovascular event, cardiovascular event, death |
Key inclusion & exclusion criteria
| Age minimum | 40years-old |
|---|---|
| Age maximum | 85years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | recurred symptomatic cerebral infarction medicatin of antiplatelet drugs before onset moyamoya disease, AVM, AN, dural AVF previous cerebral contusion previous craniotomy and/or burr hole surgery future surgery and/or intervention for brain and heart previous symptomatic cerebral hemorrhage, other hemorrhagic disease, coagulopathy present malignancy platelet count<10000/m3 liver dysfunction (AST>100IU/L, ALT>100IU/L) renal dysfunction (Cre>3mg/dl) future moving, diffculties for follow-up amyloid angiopathy participants in other intervening clinical research |
Related Information
| Primary Sponsor | SCIENCE Study Protocol Comittee |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | none |
| Secondary ID(s) |
Contact
| public contact | |
| Name | |
| Address | Japan |
| Telephone | |
| science@kuhp.kyoto-u.ac.jp | |
| Affiliation | SCIENCE Study Group SCIENCE Study office |
| scientific contact | |
| Name | Nobuo Hashimoto |
| Address | 5-7-1 Fujishiro-dai, Suita, Osaka 565-8565 Japan |
| Telephone | |
| Affiliation | Graduate School of Medicine Kyoto University (present National Cardiovascular Center) Department of Neurosurgery |